Almased: Clinical Evidence Confirms Broad Health Benefits Beyond Weight Loss
Two recent peer-reviewed reviews of clinical studies have confirmed that Almased—a high-protein, low-glycemic meal replacement—provides significant health benefits. These range from effective weight loss and improved metabolic health to anti-aging effects and enhanced quality of life.
30 Peer-Reviewed Studies Over Three Decades
Both systematic reviews summarize findings from 30 peer-reviewed clinical trials conducted over the past 30 years. The consistent conclusion: Almased is both effective and safe for a wide range of individuals. The product supports weight reduction, helps maintain muscle mass, and contributes positively to cardiovascular health.
A 2025 review published in the American Journal of Biomedical Science & Research highlights Almased’s efficacy across various populations. These include individuals seeking weight loss, those with metabolic syndrome or fatty liver disease, older adults aiming to preserve lean muscle mass, athletes, and even individuals with normal body weight who need additional high-quality protein.
The Science Behind Almased’s Formula
Almased’s formulation consists of non-GMO soy protein, yogurt, and honey. What sets it apart is its unique patented fermentation process, which leads to the formation of over 80 bioactive peptides—substances known to have positive biological effects on metabolism and cellular function.
Notably, this process produces more than twice the amount of spermidine compared to what is typically consumed through a standard diet. Spermidine is a naturally occurring compound associated with extended lifespan, improved heart health, and better brain function.
According to the review, “During Almased’s proteolytic enzymatic fermentation process, bioactive and biogenic peptides are formed that are not detectable in the raw ingredients. It is believed that the production process plays a key role in the development of compounds that drive the unexpectedly positive metabolic effects—even in individuals who are not overweight.”
Key Findings From Clinical Studies
A number of significant results emerged from studies published in journals like Heliyon and others:
Enhanced Satiety and Hormone Response
In a study by Oliveira et al. (2022), Almased led to a:
- 167% increase in GLP-1, a hormone that enhances insulin secretion and helps regulate blood sugar.
- 358% increase in PYY, a gut-derived hormone that promotes satiety.
These effects were compared to an isocaloric (equal-calorie) standard American diet and measured in the same individuals, showing a significant edge for Almased in controlling hunger and glucose metabolism.
Superior Weight and Fat Loss
In a 12-week randomized trial (Röhling et al., 2020), participants consuming Almased lost:
- 145% more total weight than the control group (-5.9 kg vs. -2.4 kg).
- 181% more fat mass (-4.5 kg vs. -1.6 kg), despite similar starting weights between the groups.
Improved Body Composition
- A 2008 study (König et al.) found a 239% greater reduction in waist circumference in the Almased group compared to those on a fat-reduced diet (-6.1 cm vs. -1.8 cm).
- Fat mass loss in the Almased group was over 82% higher (-5.1 kg vs. -2.8 kg) within just six weeks.
Muscle Mass Preservation and Increased Strength
- In a study combining Almased with resistance training (Deibert et al., 2010), participants saw a 33% increase in muscle strength over those who trained without the supplement.
- An earlier study (Deibert et al., 2004) demonstrated 100% preservation of muscle mass during weight loss, a rare and valuable outcome for those trying to lose fat without sacrificing lean tissue.
Special Benefits for At-Risk Populations
Almased has also shown remarkable results in specific populations:
Postmenopausal Women
A 2007 study (Deibert et al.) involving postmenopausal women revealed:
- A 62% reduction in the prevalence of metabolic syndrome.
- Significant fat loss without any loss of muscle mass—crucial for women in this age group, who are particularly prone to sarcopenia (age-related muscle loss).
Liver Health and Inflammation
A 2019 study by Deibert et al. found that Almased:
- Reduced liver fat content by an average of 56%.
- Helped lower markers of chronic low-grade inflammation, a known driver of many modern chronic diseases.
Improved Fat Oxidation and Metabolic Function
Research by Oliveira et al. (2021) confirmed that Almased significantly enhances fat oxidation, allowing the body to burn fat and calories more efficiently. In overweight and obese individuals, the Almased diet led to:
- Greater reductions in body weight, BMI, and fat mass.
- Improved blood sugar regulation and healthier blood lipid levels compared to standard low-calorie diets.
Support for Diabetes and Blood Sugar Control
Beyond weight regulation, Almased has shown benefits for blood glucose management in both prediabetic individuals and those with type 2 diabetes. Its low glycemic index and protein-rich composition help stabilize blood sugar levels, reducing spikes and crashes.
Anti-Aging and Cellular Health Effects
The reviews also draw attention to Almased’s anti-aging potential. Regular use has been linked to:
- Improved cellular function
- Reduced oxidative stress and inflammation
- A positive impact on energy, mood, and cognitive performance
This is largely attributed to its unique nutrient profile, including all essential amino acids and various bioactive peptides, which support cell regeneration, immune function, and overall vitality.
A Holistic Approach to Health and Longevity
The authors of the 2025 review summarize:
“The presented findings underscore the effectiveness of the soy-yogurt-honey formula (Almased) in promoting weight loss and improving cardiovascular conditions and metabolic risk factors associated with obesity.”
With robust evidence from 30 clinical studies, Almased stands out not just as a meal replacement, but as a multi-functional nutritional intervention. It supports weight loss, protects muscle mass, enhances hormonal balance, reduces inflammation, and contributes to healthier aging—offering a comprehensive solution for those seeking long-term well-being.
About Almased
Almased was developed over 30 years ago in Germany by naturopath Hubertus Trouillé and his son André Trouillé. It is a family-run company dedicated to promoting health and well-being around the world. Recognized as Europe’s leading scientifically based brand of meal replacement shakes for weight loss, Almased combines natural ingredients with a patented fermentation process to deliver high-quality, effective nutrition.
With more than 30 scientific studies conducted over three decades, Almased is a global leader in the field of metabolic health. Committed to sourcing the highest-quality ingredients worldwide, Almased continues its mission to help people live healthier and happier lives through effective, science-backed products.
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